The Isuzu Ascender was a mid-size SUV built by General Motors for Isuzu. Introduced for the 2003 model year, the 7-passenger Ascender was a re-badged GMC Envoy. It replaced the Japanese built mid-size Isuzu Trooper. A shorter 5-passenger model was made available for the 2005 model year as a replacement for the Rodeo and the Axiom. A Displacement on Demand V8 was introduced in 2005. Isuzu once offered a wide line of trucks, cars, and SUVs but the Ascender was Isuzu's last and only passenger vehicle until the introduction of the also slow-selling Isuzu i-Series pickup trucks, which were also built by GM in North America. The Ascender was never sold in Canada as Isuzu had announced, at the time, its withdrawal from there.
The Ascender ended production on June 6, 2008, as part of Isuzu's withdrawal from the United States market.