For the 2007 model year, the RX received a mid-cycle refresh consisting of a new 3.5-liter
2GR-FE V6, updating the vehicle's name from RX 330 to RX 350. The RX 350 also featured an updated, Lexus Generation V DVD navigation system. There is no on board programming procedure for the keyless entry remote fob smart key for this vehicle, therefore special equipment is required in order to program the keyless entry remote fob smart key.